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Sodium channels gone wild: resurgent current from neuronal and muscle channelopathi

18. Liu X, et al. Cutting edge: a critical role of B and T lymphocyte attenuator in peripheral T cell tolerance induction. J Immunol. 2009;182(8):4516–4520. Liakou CI, et al. CTLA-4 blockade increases IFNgamma-producing CD4+ICOShi cells to shift the ratio of ...

JCI - Putting the brakes on BTLA in T cell–mediated cancer immunothera

Recently, B and T lymphocyte attenuator (BTLA) was identified as a novel inhibitory receptor with structural and functional similarities to CTLA-4 and PD-1. ...

Role of gamma‐delta ( γδ ) T cells in autoimmuni

autoimmune hepatitis, aly/aly = alymphoplastic mutation, BTLA = B- and T-lymphocyte attenuator, CD30L = cluster of differentiation 30 ligand, CIA = collagen-induced arthritis, CSF = cerebrospinal fluid, ...

Low B and T lymphocyte attenuator expression on CD4+ T cells in the early stage of sepsis is associated with the severity and mortality of septic .

Introduction B and T lymphocyte attenuator (BTLA) is an inhibitory receptor, whose primary role in CD4 + T cell is thought to inhibit cytokine production. We explore BTLA expression on CD4 + T cells in healthy controls and septic patients, and assess the ...

B and T lymphocyte attenuator regulates CD8+ T cell–intrinsic homeostasis and memory cell generation | Nature Immunolo

B and T lymphocyte attenuator regulates CD8 + T cell–intrinsic homeostasis and memory cell generation B and T lymphocyte attenuator regulates CD8 + T cell–intrinsic homeostasis and memory cell generation ...

Academic Journa

Abstract: To investigate the peripheral blood levels of B and T lymphocyte attenuator (BTLA/CD272) on T cells and its role in Behçet disease (BD), and to define the role of inhibitory receptors on BD. Materials and methods: Included in this study were 25 patients ...

Human B-and T-lymphocyte Attenuator (BTLA) ELISA K

1 Human B-and T-lymphocyte Attenuator (BTLA) ELISA Kit Catalog Number. CSB-EL002868HU For the quantitative determination of human B-and T-lymphocyte attenuator (BTLA) concentrations in serum, plasma, tissue homogenates. This package insert ...

B and T lymphocyte attenuator expression on CD4+ T-cells associates with sepsis and subsequent infections in ICU patients | SpringerLi

B and T lymphocyte attenuator... Skip to main content Skip to sections Advertisement Hide SpringerLink Search SpringerLink Search Home Log in Critical Care Download PDF Critical Care December 2013, 17:R276 | Cite as B and T lymphocyte attenuator ...

Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required ...-2 - ScienceDire

We recently identified a novel co-stimulatory molecule, B and T lymphocyte attenuator (BTLA), ... In analyzing BTLA-deficient mice, we found evidence for an inhibitory role of BTLA in lymphocytes based upon increased antibody responses and heightened. ...

ORIGINAL ARTICLE Expression of B and T lymphocyte attenuator (BTLA) in macrophages contributes to the fulminant hepatitis caused by murine .

Expression of B and T lymphocyte attenuator (BTLA) in macrophages contributes to the fulminant hepatitis ... role in FH has yet to be investigated. Design BTLA-deficient (BTLA /) mice and their wild-type littermates were infected with murine hepatitis ...

T Cells the usual subse

protein 1; BTLA, B and T lymphocyte attenuator; CBL-B, Casitas B-lineage lymphoma B; CCL, CC-chemokine ligand; CCR, CC-chemokine receptor; CRTH2, chemoattractant receptor ...

BTLA - B- and T-lymphocyte attenuator precursor - Homo sapiens (Human) - BTLA gene & prote

B- and T-lymphocyte attenuator Gene BTLA Organism Homo sapiens (Human) Status Reviewed-Annotation score: -Experimental evidence at protein level ...

Targeting lymphocyte co-stimulation: From bench to bedside: Autoimmunity: Vol 43, No

T and B lymphocytes are central regulators and effectors of immune responses and are believed to have a key role in many autoimmune diseases. Targeting the activation or effector function of lymphocytes is a potentially effective approach to treat autoimmunity.

The opposing roles of CD4+ T cells in anti‐tumour immuni

role of CD4+ T cells is therefore to modulate the state and function of other immune cells. CD4+ T cells represent a ... (MMPs) and lower levels of co-inhibitory receptors lymphocyte activation gene 3 (LAG3), B and T lymphocyte attenuator (BTLA) and tion of+ ...

PositiveandNegativeRegulationofCellularImmuneResponses inPhysiologicConditionsandDiseas

CD278), and B- and T-lymphocyte attenuator (BTLA; CD272); (2) CD2/signaling lymphocyte activation molecule (SLAM) family ... T cells play an important role in the defense against infec-tious agents and tumors. Upon recognition of their cognate antigen, na¨ıve ...

ASSOCIATE EDITOR: MICHAEL G. ROSENBLUM Dendritic Cells as Pharmacological Tools for Cancer Immunothera

c. B and T lymphocyte attenuator. .....745 d. Immunosuppressive cells. .....745 2. Enhancing Natural Killer Cell–Mediated Antitumor Immunity.....745 C. Making Tumor Cells Susceptible to Immune Attack (Condition Number 3).....746 ...

Low B and T lymphocyte attenuator expression on CD4+ T cells in the early stage of sepsis is... - Europe PMC Article - Europe P

Introduction B and T lymphocyte attenuator (BTLA) is an inhibitory receptor, whose primary role in CD4 + T cell is thought to inhibit cytokine production. We explore BTLA expression on CD4 + T cells in healthy controls and septic patients, and assess the ...

B and T lymphocyte attenuator inhibits LPS-induced endotoxic shock by suppressing Toll-like receptor 4 signaling in innate immune cel

B and T lymphocyte attenuator inhibits LPS-induced endotoxic shock by suppressing Toll-like receptor 4 signaling in innate immune cells Yoshihisa Kobayashi a,1, ...

High Expression of the Inhibitory Receptor BTLA in T-Follicular Helper Cells and in B-Cell Small Lymphocytic Lymphoma/Chronic Lymphocytic Leukemia .

B- and T-lymphocyte attenuator (BTLA) is a lymphoid receptor that inhibits lymphocyte activation on interaction with its ligand, herpesvirus entry mediator (HVEM). ...

Characterisation of cell functions and receptors in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) | BMC Immunology | Full Te

Background Abnormal immune function is often an underlying component of illness pathophysiology and symptom presentation. Functional and phenotypic immune-related alterations may play a role in the obscure pathomechanism of Chronic Fatigue Syndrome ...